Liporase Hyaluronidase is an injectable enzyme used to break down hyaluronic acid (HA) in the skin. It is commonly used in aesthetic medicine to dissolve dermal fillers or to improve the diffusion of injected solutions. Liporase is widely used by aesthetic practitioners to correct overfilled areas, asymmetry, or complications from hyaluronic acid fillers. Active Ingredient Hyaluronidase – 1500 IU Hyaluronidase is an enzyme that: Breaks down hyaluronic acid molecules Increases tissue permeability Helps dissolve HA-based dermal fillers Main Uses • Dissolving hyaluronic acid dermal fillers • Correcting overfilled or uneven filler results • Emergency treatment of vascular occlusion caused by HA fillers • Improving absorption of injected solutions Clinical Applications Correction of lip filler complications Removal of unwanted filler volume Treatment of Tyndall effect (bluish discoloration) Emergency management in aesthetic practice Preparation Liporase usually comes as a powder vial (1500 IU) and must be reconstituted. Common dilution: 1500 IU Liporase + 3–10 ml normal saline Example concentrations: 150 IU per ml 300 IU per ml (depending on treatment) Injection Depth Depends on treatment area: Superficial dermis – for small corrections Deep dermis / subcutaneous – for larger filler deposits Important Safety Notes ⚠️ Should only be used by trained medical professionals. Possible reactions: Swelling Redness Mild burning sensation Rare allergic reactions A skin allergy test is often recommended before use. Packaging 1500 IU per vial Powder form for reconstitution Sterile vial in box